The GREAT web portal

GREAT (Genome REgulatory Architecture Tools) is an "umbrella" term for a computational schema which relates genome layout and folding to transcriptional control. It is currently under development and is divided in two parts, GREAT:SCAN and GREAT:CAD, aiming respectively at analyzing periodic patterns along genomes and at improving genome engineering by using positional information. For more specific information about the tools (usage, references, etc.), please take a look at the documentation.

The GREAT portal web application is powered by Flask, JavaScript (Highcharts, D3.js, jQuery) and Bootstrap. The web tools are benefiting from the computing resources of the iSSB abSYNTH synthetic biology platform.

How to cite

To cite GREAT, please refer to the following publication:

GREAT: a web portal for Genome Regulatory Architecture Tools
Costas Bouyioukos, François Bucchini, Mohamed Elati* and François Képès*
Nucleic acids research, gkw384, 2016 NAR

The MEGA team

The MEGA team (led by Pr. François Képès and located at the iSSB) analyzes topology, dynamics and spatial development of complex biological networks, the functional organization of cell nucleus/nucloid and of chromosomes.

If you wish to learn more, you might be interested by taking a look at the group's page on the iSSB website.


This portal is being developed by François Bucchini, Costas Bouyioukos, Mohamed Elati and François Képès.

Last update of the web portal: 4th of April 2017.

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